An unsupervised XAI framework for dementia detection with context enrichment
Published in Scientific reports, 15, 1 (2025), 2025
This work introduces a framework that evaluates XAI methods by integrating neuroanatomical morphological features with CNN-generated relevance maps for disease classification. We trained a CNN using brain MRI scans from six cohorts: ADNI, AIBL, DELCODE, DESCRIBE, EDSD, and NIFD (N = 3253), including participants that were cognitively normal, with amnestic mild cognitive impairment, dementia due to Alzheimer’s disease and frontotemporal dementia Read more
Recommended citation: Singh, D., Brima, Y., Levin, F., Becker, M., Hiller, B., Hermann, A., Villar-Munoz, I., Beichert, L., Bernhardt, A., Buerger, K. and Butryn, M., 2025. An unsupervised XAI framework for dementia detection with context enrichment. Scientific reports, 15(1), p.39554 https://doi.org/10.1038/s41598-025-26227-2
